Ivana Amajoh-Anunobi – IvanaMd https://ivanamd.com Gynecology, Sexual Health and Aesthetics Wed, 24 Jun 2026 21:27:03 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 The Link Between PCOS and Weight Gain https://ivanamd.com/the-link-between-pcos-and-weight-gain/?utm_source=rss&utm_medium=rss&utm_campaign=the-link-between-pcos-and-weight-gain Wed, 24 Jun 2026 21:26:55 +0000 https://ivanamd.com/?p=13894 PCOS and weight gain are closely linked through insulin resistance, hormonal imbalances, and metabolic changes that make losing weight more difficult. Understanding the underlying causes of PCOS-related weight gain can help women pursue effective treatments that improve hormone balance, support weight loss, and restore overall reproductive health.

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Women’s Health | IVANA MD | Missouri City, TX

If you have been struggling to lose weight despite eating well and exercising, and you also deal with irregular periods, acne, or excess hair growth, polycystic ovary syndrome may be the missing piece of the puzzle. PCOS and weight gain are deeply connected, and understanding why makes all the difference in how you approach treatment.

What Is PCOS?

Polycystic ovary syndrome, commonly known as PCOS, is one of the most common hormonal disorders affecting women of reproductive age, impacting an estimated 8 to 13 percent of women worldwide according to the World Health Organization. It is characterized by hormonal imbalances, irregular menstrual cycles, elevated androgen levels, and in many cases the development of small cysts on the ovaries.

Why Does PCOS Cause Weight Gain?

The relationship between PCOS and weight gain is not simply about lifestyle. It is rooted in biology. The primary driver is insulin resistance, a condition in which the body’s cells do not respond properly to insulin, causing the pancreas to produce more of it. Excess insulin promotes fat storage, particularly around the abdomen, and makes losing weight significantly harder regardless of diet or exercise habits.

A study published in the Journal of Clinical Endocrinology and Metabolism found that up to 70 percent of women with PCOS have some degree of insulin resistance, even those who are not overweight. This means the weight struggle is not a matter of willpower. It is a metabolic issue that requires targeted medical support.

The Hormonal Cycle Making It Worse

PCOS creates a frustrating cycle. Excess weight worsens insulin resistance, which raises insulin levels further, which in turn drives up androgen production, which disrupts ovulation and worsens PCOS symptoms. Research published in Human Reproduction confirms that even a modest weight gain can significantly worsen hormonal imbalances in women with PCOS, while even a 5 to 10 percent reduction in body weight can restore ovulation, improve insulin sensitivity, and reduce androgen levels.

Other Reasons Weight Management Is Harder with PCOS

Beyond insulin resistance, several other factors make weight management more challenging for women with PCOS, including:

  • Elevated cortisol levels, which promote abdominal fat storage
  • Low-grade chronic inflammation, which interferes with metabolism
  • Disrupted hunger hormones, with research showing women with PCOS have altered levels of ghrelin and leptin, the hormones that regulate appetite and fullness
  • Sleep disturbances and fatigue, which are common in PCOS and directly affect metabolism and food choices

What the Science Says About Treatment

Managing weight with PCOS requires a strategy that addresses the hormonal root cause, not just calories. Evidence-based approaches include:

  • A low glycemic index diet, which reduces insulin spikes and has been shown in multiple studies to improve both weight and hormonal markers in women with PCOS
  • Regular resistance training combined with cardio, which improves insulin sensitivity and supports healthy body composition
  • Metformin, a medication that improves insulin sensitivity and is commonly prescribed for PCOS-related weight and metabolic issues
  • Inositol supplements, particularly myo-inositol, which a review in the International Journal of Endocrinology found to significantly improve insulin resistance, hormone levels, and menstrual regularity in women with PCOS
  • GLP-1 receptor agonists, which are emerging as an effective option for women with PCOS and significant insulin resistance or obesity

When to See a Doctor

If you suspect PCOS is behind your weight struggles, a diagnosis is the critical first step. A women’s health provider can run hormonal panels, check insulin and glucose levels, perform an ultrasound, and create a personalized treatment plan that addresses both your metabolic health and your reproductive health together.

You are not failing at weight loss. Your hormones may simply be working against you, and that is something a doctor can help you fix.

๐Ÿ“ Schedule your women’s health appointment with IVANA MD in Missouri City, TX. 

๐Ÿ“ž 346-585-4077. 4220 Cartwright Road, Suite 201, Missouri City, Texas 77459.

References

Azziz, R., Carmina, E., Dewailly, D., et al. (2016). Polycystic ovary syndrome. Nature Reviews Disease Primers, 2(1), 16057.https://www.nature.com/articles/nrdp201657

Dunaif, A. (1997). Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. Endocrine Reviews, 18(6), 774โ€“800. https://academic.oup.com/edrv/article/18/6/774/2530788

Kiddy, D. S., Hamilton-Fairley, D., Bush, A., et al. (1992). Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome. Clinical Endocrinology, 36(1), 105โ€“111. https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2265.1992.tb02909.x 

Unfer, V., Carlomagno, G., Dante, G., & Facchinetti, F. (2012). Effects of myo-inositol in women with PCOS: a systematic review of randomized controlled trials. Gynecological Endocrinology, 28(7), 509โ€“515. https://www.tandfonline.com/doi/abs/10.3109/09513590.2011.650660 

World Health Organization. (2026). Polycystic ovary syndrome. WHO Fact Sheets. https://www.who.int/news-room/fact-sheets/detail/polycystic-ovary-syndrome

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What to Expect After IUD Insertion https://ivanamd.com/what-to-expect-after-iud-insertion/?utm_source=rss&utm_medium=rss&utm_campaign=what-to-expect-after-iud-insertion Tue, 23 Jun 2026 15:27:03 +0000 https://ivanamd.com/?p=13890 After IUD insertion, mild cramping, spotting, dizziness, and irregular bleeding are common and usually improve within days or months. Hormonal and copper IUDs have different adjustment periods, but both are highly effective. Knowing what is normal and when to seek medical care can help ensure a smooth recovery.

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Women’s Health | IVANA MD | Missouri City, TX

If you have just had an IUD inserted or are considering one, knowing what to expect afterward can make the experience much less stressful. IUDs are one of the most effective forms of long-acting reversible contraception available, but the days and weeks following insertion come with an adjustment period every woman should be prepared for.

What Is an IUD?

An intrauterine device is a small T-shaped device inserted into the uterus to prevent pregnancy. There are two main types: hormonal IUDs, which release a small amount of progestin, and copper IUDs, which are completely hormone-free. Both are over 99 percent effective according to the Centers for Disease Control and Prevention.

Immediately After Insertion

In the first few hours it is completely normal to experience:

  • Moderate to severe cramping
  • Dizziness or lightheadedness
  • Light spotting or bleeding
  • Nausea or pelvic heaviness

These symptoms typically ease within a few hours. Take ibuprofen before and after the procedure and plan to rest for the remainder of the day.

The First One to Three Months

With a hormonal IUD expect irregular spotting for the first three to six months, with periods gradually becoming lighter over time. With a copper IUD expect heavier periods and stronger cramping, particularly in the first few months. Research published in Contraception journal confirms that most bleeding irregularities resolve on their own with time.

Signs of Complications to Watch For

While serious complications are rare, contact your provider immediately if you experience:

  • Severe pelvic pain that worsens after the first few days
  • Heavy bleeding soaking through more than one pad per hour
  • Fever, chills, or unusual discharge
  • Pain during sex
  • You can feel the hard plastic of the IUD

When Does It Become Effective?

Hormonal IUDs are effective immediately if inserted within the first seven days of your cycle. Otherwise use a backup method for seven days. Copper IUDs are effective immediately and can even be used as emergency contraception within five days of unprotected sex.

An IUD is a highly effective long-term option, but it should always feel like the right fit for your body and your life.

๐Ÿ“ Schedule your women’s health appointment with IVANA MD in Missouri City, TX. 

๐Ÿ“ž 346-585-4077

4220 Cartwright Road, Suite 201, Missouri City, Texas 77459.

References

Centers for Disease Control and Prevention. (2024). Intrauterine contraception. U.S. Selected Practice Recommendations for Contraceptive Use (U.S. SPR). https://www.cdc.gov/contraception/hcp/usspr/intrauterine-contraception.html 

ESHRE Capri Workshop Group. (2008). Intrauterine devices and intrauterine systems. Human Reproduction Update, 14(3), 197โ€“208. https://academic.oup.com/humupd/article/14/3/197/683294

Heinemann, K., Reed, S., Moehner, S., & Minh, T. D. (2015). Comparative contraceptive effectiveness of levonorgestrel-releasing and copper intrauterine devices: The European Active Surveillance Study for Intrauterine Devices. Contraception, 91(4), 280โ€“283.https://pubmed.ncbi.nlm.nih.gov/25601350/ 

Hidalgo, M., Bahamondes, L., Perrotti, M., et al. (2002). Bleeding patterns and clinical performance of the levonorgestrel-releasing intrauterine system (Mirena) up to two years. Contraception, 65(2), 129โ€“132. https://pubmed.ncbi.nlm.nih.gov/11927115/ 

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What Is a Uterine Abnormality? https://ivanamd.com/what-is-a-uterine-abnormality/?utm_source=rss&utm_medium=rss&utm_campaign=what-is-a-uterine-abnormality Mon, 22 Jun 2026 18:04:36 +0000 https://ivanamd.com/?p=13887 A uterine abnormality is a structural or functional irregularity of the uterus that may be present at birth or develop later in life. Conditions such as fibroids, polyps, septate uterus, and adenomyosis can affect menstruation, fertility, pregnancy outcomes, and overall reproductive health.

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Women’s Health | IVANA MD | Missouri City, TX

The uterus plays a central role in menstruation, fertility, and pregnancy. When its structure or function deviates from normal, it is referred to as a uterine abnormality. These conditions are more common than most women realize and can range from minor variations that cause no symptoms to significant structural differences that affect reproductive health and quality of life.

Uterine Abnormality

A uterine abnormality is any structural, functional, or anatomical irregularity of the uterus. These can be congenital, meaning present from birth due to abnormal development of the Mรผllerian ducts during fetal development, or acquired, meaning they develop later in life due to growths, scarring, or hormonal changes.

Types of Uterine Abnormalities

Congenital Uterine Abnormalities

Congenital uterine abnormalities occur when the Mรผllerian ducts, which form the uterus, fallopian tubes, and upper vagina during fetal development, do not develop or fuse properly. The most common types include:

  • Septate uterus, where a fibrous band of tissue divides the uterine cavity partially or completely and is the most common congenital abnormality, accounting for up to 35 percent of cases according to research in Fertility and Sterility
  • Bicornuate uterus, where the uterus has two distinct horns or cavities giving it a heart-shaped appearance
  • Unicornuate uterus, where only one side of the Mรผllerian duct develops, resulting in a smaller, single-horned uterus
  • Didelphys uterus, where the ducts fail to fuse entirely resulting in a double uterus sometimes accompanied by a double cervix
  • Arcuate uterus, a mild indentation at the top of the uterine cavity considered by many to be a normal variant

Acquired Uterine Abnormalities

Acquired abnormalities develop after birth and include:

  • Uterine fibroids, which are noncancerous muscular growths that can distort the shape and size of the uterus and affect up to 70 percent of women by age 50 according to the Office on Women’s Health
  • Endometrial polyps, which are soft tissue growths on the inner lining of the uterus that can cause irregular bleeding and interfere with implantation
  • Asherman syndrome, a condition where scar tissue or adhesions form inside the uterine cavity, often following surgery, infection, or repeated dilation and curettage procedures
  • Adenomyosis, where the tissue that normally lines the uterus grows into the muscular wall, causing the uterus to enlarge and become tender

What Are the Symptoms?

Many women with uterine abnormalities have no symptoms at all and only discover the condition during a routine exam or when investigating fertility issues. When symptoms do occur they may include:

  • Abnormal uterine bleeding including heavy, prolonged, or irregular periods
  • Pelvic pain or pressure
  • Painful periods
  • Recurrent miscarriages
  • Difficulty conceiving
  • Preterm labor or pregnancy complications
  • Pain during sex

What Does Science Say?

Research published in Human Reproduction found that congenital uterine abnormalities are present in approximately 5.5 percent of the general population but are significantly more prevalent among women with recurrent pregnancy loss, affecting up to 13 percent of that group. A study in Fertility and Sterility also found that women with a septate uterus had significantly higher rates of miscarriage and preterm birth compared to women with a normal uterine cavity, but that surgical correction of the septum substantially improved pregnancy outcomes.

How Are Uterine Abnormalities Diagnosed?

Several imaging and diagnostic tools are used to identify uterine abnormalities, including:

  • Pelvic ultrasound, which is typically the first imaging tool used
  • Sonohysterography, which uses saline solution and ultrasound to better visualize the uterine cavity
  • Hysteroscopy, which allows direct visualization of the inside of the uterus using a small camera
  • MRI, which provides the most detailed and accurate imaging of uterine structure and is considered the gold standard for diagnosing congenital abnormalities

Can Uterine Abnormalities Be Treated?

Treatment depends on the type of abnormality, the severity of symptoms, and your reproductive goals. Options include:

  • Hysteroscopic surgery to remove a uterine septum, polyps, fibroids, or adhesions
  • Myomectomy to remove fibroids while preserving the uterus
  • Hormonal therapy to manage symptoms related to adenomyosis or fibroids
  • Endometrial ablation for abnormal bleeding in women who do not wish to conceive
  • Hysterectomy in severe cases where other treatments have not been effective

Many women with uterine abnormalities go on to have successful pregnancies, particularly when the condition is identified and treated early.

When to See a Doctor

You should speak with a women’s health provider if you are experiencing heavy or irregular periods, recurrent miscarriages, difficulty conceiving, chronic pelvic pain, or painful intercourse. A thorough evaluation can determine whether a uterine abnormality is contributing to your symptoms and what treatment options are available to you.

A diagnosis is not a dead end. For most uterine abnormalities, effective treatment exists and outcomes with proper care are very encouraging.

๐Ÿ“ Schedule your women’s health appointment with IVANA MD in Missouri City, TX. 

๐Ÿ“ž 346-585-4077. 

4220 Cartwright Road, Suite 201, Missouri City, Texas 77459.

References

Aciรฉn, P. (1993). Reproductive performance of women with uterine malformations. Human Reproduction, 8(1), 122โ€“126.https://pubmed.ncbi.nlm.nih.gov/8458914/

Grimbizis, G. F., Camus, M., Tarlatzis, B. C., et al. (2001). Clinical implications of uterine malformations and hysteroscopic treatment results. Human Reproduction Update, 7(2), 161โ€“174.https://pubmed.ncbi.nlm.nih.gov/11284660/

Office on Women’s Health. (2025). Uterine fibroids. U.S. Department of Health and Human Services. https://www.womenshealth.gov/a-z-topics/uterine-fibroids

Saravelos, S. H., Cocksedge, K. A., & Li, T. C. (2008). Prevalence and diagnosis of congenital uterine anomalies in women with reproductive failure: a critical appraisal. Human Reproduction Update, 14(5), 415โ€“429. https://pubmed.ncbi.nlm.nih.gov/18539641/

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How to Improve Sexual Health After Childbirth https://ivanamd.com/how-to-improve-sexual-health-after-childbirth/?utm_source=rss&utm_medium=rss&utm_campaign=how-to-improve-sexual-health-after-childbirth Fri, 19 Jun 2026 15:59:21 +0000 https://ivanamd.com/?p=13881 Learn how to improve sexual health after childbirth, including treatments for vaginal dryness, low libido, pelvic floor dysfunction, and painful sex. Discover evidence-based postpartum recovery strategies and women's health support from IVANA MD in Missouri City, Texas.

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Women’s Health | IVANA MD | Missouri City, TX

Returning to a satisfying sex life after having a baby is something many women struggle with but few feel comfortable talking about openly. Changes in desire, physical discomfort, hormonal shifts, and emotional exhaustion are all real and valid parts of the postpartum experience. The good news is that with the right information and support, sexual health after childbirth can absolutely be restored and even improved.

Why Sex Changes After Childbirth

The postpartum body goes through a significant hormonal transition. Estrogen and progesterone drop sharply after delivery, and if you are breastfeeding, prolactin levels remain elevated while estrogen stays low. This hormonal environment closely mimics menopause and directly causes vaginal dryness, thinning of vaginal tissue, reduced libido, and pain during sex. A study published in the Journal of Sexual Medicine found that up to 83 percent of women reported sexual problems in the first three months postpartum, with many experiencing difficulties that persisted well into the first year.

Common Sexual Health Challenges After Childbirth

  • Vaginal dryness and atrophy due to low estrogen
  • Pain during intercourse, known as dyspareunia
  • Reduced or absent libido
  • Perineal soreness or scar tissue from tearing or episiotomy
  • Pelvic floor dysfunction including weakness or excessive tension
  • Body image concerns and emotional disconnect
  • Fatigue and sleep deprivation affecting desire and intimacy

When Is It Safe to Resume Sex?

Most healthcare providers recommend waiting at least six weeks after delivery before resuming penetrative sex, allowing time for the cervix to close, any tears or incisions to heal, and postpartum bleeding to stop. However, research published in BJOG: An International Journal of Obstetrics and Gynecology found that readiness varies widely among women and that emotional and physical preparedness matters just as much as the timeline. There is no universal rule and open communication with your partner and provider is key.

How to Improve Sexual Health Postpartum

Address Vaginal Dryness

Low estrogen after childbirth causes vaginal dryness that makes sex uncomfortable or painful. Using a high quality water-based lubricant during sex provides immediate relief. For longer term improvement, your doctor may recommend a topical vaginal estrogen cream or suppository, which research in Menopause journal has shown to effectively restore vaginal tissue health with minimal systemic absorption, making it safe even for breastfeeding women.

Invest in Pelvic Floor Therapy

The pelvic floor takes a significant hit during pregnancy and delivery. Whether your muscles are weakened or have become overly tight and tense, both conditions affect sexual function and comfort. Pelvic floor physical therapy is one of the most evidence-based postpartum interventions available. A study in the International Urogynecology Journal found that pelvic floor rehabilitation significantly improved sexual satisfaction and reduced pain during intercourse in postpartum women. Ask your provider for a referral as early as six weeks postpartum.

Prioritize Emotional Intimacy First

Sexual desire is deeply connected to emotional wellbeing and relational safety. Before rushing back into physical intimacy, focusing on non-sexual touch, open communication with your partner, and rebuilding emotional connection creates a foundation that makes physical intimacy more natural and enjoyable. Postpartum mood disorders including anxiety and depression, which affect up to 20 percent of new mothers according to the American Psychological Association, can significantly suppress libido and should be addressed with professional support if present.

Support Hormonal Recovery

Breastfeeding prolongs the period of low estrogen, which is why many nursing mothers experience prolonged vaginal dryness and low libido. This is temporary and resolves as breastfeeding decreases or stops. In the meantime, supporting overall hormonal health through adequate sleep, a nutrient-dense diet, stress management, and regular gentle movement helps the body recover more efficiently. Once breastfeeding ends, estrogen typically rebounds and sexual function often improves naturally.

Communicate Openly with Your Partner

One of the most overlooked aspects of postpartum sexual health is communication. Many women feel pressure to return to their previous sexual patterns before they are truly ready, which can create anxiety and further reduce desire. Research consistently shows that couples who communicate openly about postpartum changes report greater sexual satisfaction and relationship quality during the transition to parenthood. Being honest about what feels good, what does not, and what you need emotionally creates space for intimacy to rebuild at a pace that works for both partners.

When to See a Doctor

You should speak with a women’s health provider if pain during sex persists beyond three to six months postpartum, if your libido has not returned after weaning from breastfeeding, if you are experiencing symptoms of postpartum depression or anxiety that are affecting your relationship and desire, or if vaginal dryness is not improving with over-the-counter lubricants. These are all treatable conditions and you do not have to navigate them alone.

Your body has been through something extraordinary. Giving yourself grace, time, and the right medical support makes all the difference.

๐Ÿ“ Schedule your women’s health appointment with IVANA MD in Missouri City, TX. 

๐Ÿ“ž 346-585-4077 

4220 Cartwright Road, Suite 201, Missouri City, Texas 77459.

References

American Psychological Association. (2022). Postpartum depression: Causes, symptoms, risk factors, and treatment. APA https://www.apa.org/topics/women-girls/postpartum-depression 

Declercq, E. R., Sakala, C., Corry, M. P., et al. (2013). Listening to Mothers III: New Mothers Speak Out. National Partnership for Women & Families Report. https://nationalpartnership.org/wp-content/uploads/2023/02/listening-to-mothers-iii-new-mothers-speak-out-2013.pdf 

Barrett, G., Pendry, E., Peacock, J., et al. (2000). Women’s sexual health after childbirth. BJOG: An International Journal of Obstetrics & Gynaecology, 107(2), 186โ€“195. https://pubmed.ncbi.nlm.nih.gov/10688502/

Hadizadeh-Talasaz, Z., Sadeghi, R., & Khadivzadeh, T. (2019). Effect of pelvic floor muscle training on postpartum sexual function and quality of life: A systematic review and meta-analysis of clinical trials. Taiwanese Journal of Obstetrics and Gynecology, 58(6), 737โ€“747. https://pubmed.ncbi.nlm.nih.gov/31759521/

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The Relationship Between Hormones and Mood https://ivanamd.com/the-relationship-between-hormones-and-mood/?utm_source=rss&utm_medium=rss&utm_campaign=the-relationship-between-hormones-and-mood Mon, 08 Jun 2026 21:17:56 +0000 https://ivanamd.com/?p=13877 Hormonal changes can affect mood, anxiety, depression, sleep, and energy levels. Learn how estrogen, progesterone, cortisol, and dopamine influence emotional health and when to seek women's health care in Missouri City, TX.

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Women’s Health | IVANA MD | Missouri City, TX

Have you ever felt irritable, anxious, or emotionally drained with no clear explanation? You’re not imagining it. Hormonal fluctuations are one of the most common and most overlooked causes of mood changes in women.

What Are Hormones Doing to Your Mood?

Hormones act as chemical messengers in the body, and several of them directly regulate how you feel emotionally:

Estrogen boosts serotonin, your brain’s natural mood stabilizer. When estrogen drops (during your period, after childbirth, or during perimenopause), serotonin follows, often triggering sadness, irritability, and anxiety.

Cortisol: your stress hormone, is helpful in short bursts but damaging when chronically elevated. Research published in Psychoneuroendocrinology links prolonged high cortisol to depression, brain fog, and poor emotional regulation.

Progesterone has a calming, sedative effect. When it falls sharply before menstruation, many women experience the mood swings associated with PMS or PMDD.

Dopamine drives motivation and pleasure. Low dopamine, often tied to hormonal imbalance, can leave you feeling flat, unmotivated, or emotionally numb.

What Does Science Say?

A 2016 study in JAMA Psychiatry found that women prone to premenstrual mood symptoms show measurable serotonin dysregulation directly tied to estrogen fluctuations. The National Institute of Mental Health also confirms that estrogen enhances serotonin receptor sensitivity, which explains why mood often deteriorates during perimenopause and postpartum periods.

Signs Your Hormones May Be Affecting Your Mood

  • Mood swings that follow your menstrual cycle
  • Anxiety or depression that worsens before your period
  • Persistent fatigue and brain fog
  • Difficulty sleeping
  • Low motivation or loss of interest in things you enjoy

These are not personality traits. They are medical symptoms with real, treatable causes.

What You Can Do

A women’s health specialist can run targeted hormone panels and create a personalized treatment plan, whether that includes hormone therapy, nutritional support, or lifestyle strategies. 

You don’t have to just “push through it.”

Schedule your women’s health appointment with IVANA MD in Missouri City, TX. 

Call: 346-585-4077 4220 

Cartwright Road, Suite 201, Missouri City, Texas 77459

References

Joffe, H., & Cohen, L. S. (1998). Estrogen, serotonin, and mood disturbance: Where is the therapeutic bridge? Biological Psychiatry, 44(9), 798โ€“811.https://www.sciencedirect.com/science/article/abs/pii/S0006322398001693

National Institute of Mental Health. (2023). Postpartum depression. https://www.nimh.nih.gov/health/publications/perinatal-depression

Rivera-Bonet, C. N., Birn, R. M., Ladd, C. O., Meyerand, M. E., & Abercrombie, H. C. (2021). Cortisol effects on brain functional connectivity during emotion processing in women with depression. Journal of Affective Disorders, 287, 247โ€“254 https://www.sciencedirect.com/science/article/abs/pii/S0165032721002603 

Steiner, M., & Pearlstein, T. (2000). Premenstrual dysphoria and the serotonin system: Pathophysiology and treatment. The Journal of Clinical Psychiatry, 61(Suppl 12), 17โ€“21.Premenstrual dysphoria and the serotonin system: pathophysiology and treatment – PubMed 

Stephens, M. A., & Wand, G. (2012). Stress and the HPA axis: Role of glucocorticoids in alcohol dependence. Alcohol Research: Current Reviews, 34(4), 468โ€“483. https://www.ncbi.nlm.nih.gov/books/NBK278995/

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